Research Animals

Summary: This paper will examine the various federal regulations on animal biomedical testing within the United States as well as the industry’s standards and trends. The first four sections examine the FDA requirements for medical products in the United States, federal animal welfare regulations, the general structure of a research facility, and industry regulations for animal use. The second half of this paper examines the species of animals used in research as well as their source of purchase. Accepted methods of euthanasia per species are also examined. By comparing the options available for a research facility to animal use regulations in the United States, it is hoped that the structure of animal welfare in the laboratory can be understood from both economic and legal motivations that influence animal research use today.

Summary: This Uganda act, in English, provides provisions for the offense of animal cruelty. The act also allows the court to order the destruction of an animal when the animal's owner has been convicted of an offense of animal cruelty if the court is satisfied it would be cruel to keep the animal alive. The court may also deprive a person convicted of cruelty ownership of the animal and order for the animal to be disposed as it thinks fit. It is also illegal to permit a diseased animal to be at large in public places; a court may also order a diseased animal at large in any public place to be destroyed. No appeal can be made against either order of destruction. The sale of poisoned grain that is to be used as feeding stuff is also an offence. Also included in this act are provisions about experiments.

Summary: Directive 2010/63/EU revises Directive 86/609/EEC on the protection of animals used for scientific purposes. It aims to replace, reduce and refine the use of animals in research procedures by using alternative approaches. The directive applies to live non-human vertebrate animals, including independently feeding larval forms and foetal forms of mammals in the last trimester, and live cephalopods. The directive also applies to animals used in procedures, which are at an earlier stage of development than that referred to above, if the animal is to be allowed to live beyond that stage of development and, as a result of the procedures performed, is likely to experience pain, suffering, distress or lasting harm after it has reached that stage of development. It also sets out provisions for risk-based inspections and lays down minimum care standards.

Summary: Ley 20.380 is the is the Chilean Animal Protection Statute. It recognizes animals as living beings and establishes the norms for the “recognition, protection and respect of animals” in order to avoid unnecessary pain and suffering. This law punishes animal cruelty with imprisonment of up to 3 years. Labs, zoos, circuses, and other establishments that keep animals for exhibition and entertainment are allowed, so long as they have the adequate facilities according to the species and adequate safety for people. Animal experimentation in schools is allowed under this law. Rodeo, rein-back and equestrian sports are excepted from provisions of this law.

Summary: The aim pursued by this Directive is to ensure the provisions laid down by law, regulation or administrative provisions in the Member States for the protection of animals used for research avoid affecting the market. In this directive, an experiment not entailing the use of animals is preferred over one that does if that experiment can obtain the same result and is reasonably and practically available. Furthermore, each Member State shall ensure that experiments using animals considered as endangered under Appendix I of the Convention on International Trade in Endangered Species of Fauna and Flora and Annex C.I of Regulation (EEC) No. 3626/82 are prohibited unless they are in conformity with the above-mentioned Regulation and the objects of the experiment are research aimed at preservation of the species in question, or essential biomedical purposes where the species in question exceptionally proves to be the only one suitable for those purposes.

Summary: After pressures from multiple animal rights organizations, an Israeli airline stopped flying monkeys to Israeli research institutions. Multiple Israeli research institutions then filed suit, asking the court to present the airline with a permanent order to fly animals as per their requests, including monkeys, for bio-medical research purposes. In the present case, the question to be decided was whether to allow several animal protection organizations to be added to the claim (whether the airline was bound to fly animals for experiments or not) as defendants or as amicus curiae. The court held that the animal protection organizations should be allowed to join the proceedings as defendants because they could bring before the court a more complete picture of the issue before it was decided; they filed their request at a very early stage; and they spoke and acted for the animals in the face of a verdict that might directly affect the legal rights of the animals.

Summary: After pressures from multiple animal rights organizations, an Israeli airline stopped flying monkeys to Israeli research institutions. Multiple Israeli research institutions then filed suit, asking the court to present the airline with a permanent order to fly animals as per their requests, including monkeys, for bio-medical research purposes. In the present case, the question to be decided was whether to allow several animal protection organizations to be added to the claim (whether the airline was bound to fly animals for experiments or not) as defendants or as amicus curiae. The court held that the animal protection organizations should be allowed to join the proceedings as defendants because they could bring before the court a more complete picture of the issue before it was decided; they filed their request at a very early stage; and they spoke and acted for the animals in the face of a verdict that might directly affect the legal rights of the animals.

Summary: Behavioral research has made significant contributions to the understanding, treatment, and prevention of behavioral disorders. Experimental animals play an essential role in this work. The National Institute of Mental Health (NIMH), together with other institutes of the National Institutes of Health (NIH) that have relevant research programs, prepared this handbook. The handbook provides a description of and references for commonly used behavioral research methods and associated animal welfare considerations in accordance with Federal laws governing animal research. It is intended to assist Institutional Animal Care and Use Committees (IACUCs) in their reviews of protocols involving animal behavior and animal cognition, particularly when expertise is not available on the committee, and to assist investigators in planning their experiments.

Summary: This report summarizes the findings and recommendations of the Working Group on the Use of Chimpanzees in National Institutes of Health (NIH)-Supported Research. The NIH formed this committee within the Council of Councils, a federal advisory committee, to advise the NIH on the implementation of the recommendations of the Institute of Medicine’s (IOM’s) Committee on the Use of Chimpanzees in Biomedical and Behavioral Research regarding the use of chimpanzees in NIH-sponsored research.

Summary: These South African regulations were made relating to listed threatened and protected species of the National Environmental Management: Biodiversity Act, 2004. The purpose of these regulations is to further regulate the permit system set out in Chapter 7 of the Biodiversity Act insofar as that system applies to restricted activities involving specimens of listed threatened or protected species; to provide for the registration of captive breeding operations, commercial exhibition facilities, game farms, nurseries, scientific institutions, sanctuaries and rehabilitation facilities and wildlife traders; to provide for the regulation of the carrying out of a specific restricted activity, namely hunting; to provide for the prohibition of specific restricted activities involving specific listed threatened or protected species; to provide for the protection of wild populations of listed threatened species; and to provide for the composition and operating procedure of the Scientific Authority.